LMOD2 attenuates Ang II-induced cardiomyocyte hypertrophy by activating the Nrf2-mediated antioxidant pathway
A new scientific study identifies LMOD2 as a protective factor against pathological cardiac hypertrophy by activating the Nrf2 antioxidant signaling pathway. Researchers found that LMOD2 overexpression reduces oxidative stress and heart cell enlargement in laboratory models.
Why it matters
This research provides potential new therapeutic targets for treating heart failure and understanding the molecular mechanisms of cardiac disease.
Scientific Reports ( 2026 ) Cite this article
We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.
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