Linking centromere stretch to SAC signaling in mammalian oocytes with insights from modified kinetochore model
Researchers have identified a correlation between centromere stretching and spindle assembly checkpoint (SAC) signaling in mammalian oocytes. The study suggests that centromere tension is a critical signal for deactivating cell-cycle checkpoints during meiosis.
Why it matters
This discovery advances the understanding of fundamental cell biology and error correction mechanisms in reproduction.
Communications Biology ( 2026 ) Cite this article
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