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ScienceDaily·3 min read·medium

Light switch wakes sleeping cancer cells and makes them vulnerable again

Light switch wakes sleeping cancer cells and makes them vulnerable again
AI Summary

Researchers at ETH Zurich have developed a light-sensitive system to wake dormant cancer cells, making them vulnerable to treatment. By targeting glucocorticoid receptors specifically in tumor cells, the method avoids the systemic side effects associated with traditional hormone-based therapies.

Why it matters

This breakthrough offers a potential pathway to treat drug-resistant cancers by preventing cells from entering a dormant, treatment-evading state.

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Some cancer cells can enter a dormant, sleep-like state that helps them survive treatment. Instead of continuing to grow and divide, these cells become largely inactive, allowing them to avoid the effects of many cancer drugs.

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