Led Heart Study Reaches Major Scientific Milestone

The THESUS-HF II study, the largest investigation into acute heart failure in Africa, has been published in The Lancet. The research highlights that heart failure in Africa disproportionately affects younger, working-age individuals and is increasingly linked to lifestyle-related coronary artery disease.
Why it matters
This study provides critical data for public health policy in Africa, identifying shifting disease patterns that require new medical interventions and resource allocation.
CAPE TOWN
An African-led investigation into acute heart failure has been completed and published in <em>The Lancet</em>, marking a major milestone for cardiovascular research on the continent.
The THESUS-HF II study was coordinated through the Pan-African Society of Cardiology, or PASCAR, with support from the University of Cape Town’s Cape Heart Institute.
Researchers collected data from more than 1,500 acute heart failure cases at 50 hospitals across 17 African countries, making it the largest study of heart failure in Africa to date, according to the institute’s announcement.
The study was led by Professor Karen Sliwa, with investigators including Dr. Julia Hahnle, Professor Simon Stewart and collaborators across the continent. It builds on findings from the original THESUS-HF study conducted more than 15 years ago.
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