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The Hindu·3 min read·hard

Landmark study offers new insights into what protects against dengue

Landmark study offers new insights into what protects against dengue
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Researchers have identified specific 'EDE-like' antibodies that may be crucial for developing broad, cross-serotype immunity against the dengue virus. This discovery offers a potential breakthrough in overcoming the complex immune challenges that have hindered universal vaccine development.

Why it matters

Dengue remains a major global health threat, and understanding these immune mechanisms is essential for creating effective, long-term vaccines.

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The specific components of the immune response in a human body that protect against a dengue virus (DENV) infection and the subsequent illness remain unclear. Scientists are still trying to understand how natural infection and vaccination protect people so that they can develop better vaccines .

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