Interpreting Kidney Donor Pregnancy Signals, With Amit Garg, MD, PhD
A Canadian study presented at ASN Kidney Week 2026 suggests that living kidney donors may face a higher risk of hypertensive disorders and small for gestational age births during pregnancy. The research compared 252 donors against a matched cohort of nondonors.
Why it matters
These findings provide critical health information for potential living kidney donors regarding long-term reproductive health outcomes.
Small for gestational age births and shared donor-recipient genetics complicate the picture of pregnancy after living kidney donation.
Investigators behind a new Canadian study of pregnancy after living kidney donation are weighing why donors had more small for gestational age (SGA) births than matched nondonors, and whether shared genetics with recipients could play a role.¹
The matched cohort study, presented at American Society of Nephrology (ASN) Kidney Week 2026 by Amit X. Garg, MD, PhD, and published simultaneously in JAMA, spanned 3 provinces and also found a modest increase in hypertensive disorders of pregnancy among donors.¹
How Did the Study Compare Donors and Nondonors?
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