IIT Kanpur researchers solve mystery of atypical drug target receptor
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Researchers at IIT Kanpur have used cryogenic-electron microscopy to map the structure of the C5aR2 immune receptor. This discovery explains why the receptor functions differently from its counterpart and aids in future drug design.
Why it matters
Understanding the molecular basis of immune receptors is critical for developing targeted therapies for inflammatory diseases and infections.
Researchers at IIT Kanpur, led by Professor Arun K Shukla, have uncovered the molecular basis underlying the atypical signalling behaviour of C5aR2, an immune receptor that has puzzled scientists for years.
The article is a technical report on scientific research with no political or social bias.
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