Human activity has shaped the genetic diversity of dengue mosquitoes in India

Scientists have analyzed the genetic diversity of Aedes aegypti mosquitoes across India to understand how human activity influences their evolution. The study highlights how urbanization, transport, and trade have shaped the mosquito's population structure and disease-spreading capabilities.
Why it matters
Understanding the genetic evolution of disease vectors is critical for developing effective public health surveillance and insecticide resistance strategies.
From its roots in Africa, the dengue-spreading mosquito , Aedes aegypti, expanded its range in the 15th century, across the world, aided by the transatlantic slave trade between Africa, America and Europe. And by the late 19th century the insect, with its great environmental adaptability, reached India: in 2024 the country recorded around 2,50,000 dengue cases.
Today, Aedes aegypti, the main vector of chikungunya, yellow fever and Zika too, has spread to almost every environment in India: deserts, tropical forests, urban jungles, and recently, in certain rural areas where they were never found before.
Now for the first time, scientists scoured the country, sampled 126 mosquitoes from 13 regions, to better understand the evolution of this mosquito’s genetic diversity. An understanding of this heterogeneity is vital, said a paper published in Acta Tropica , as genetic diversity also influences the ability of mosquitoes in spreading disease or resisting insecticides.
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