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The Hindu·4 min read·medium

How protein biosensors can shrink the timeline of medical emergencies

M
Manjeera Gowravaram
How protein biosensors can shrink the timeline of medical emergencies
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Researchers are developing compact protein biosensors capable of detecting immune proteins in blood in real time to diagnose conditions like sepsis. This technology aims to replace standard blood tests that can take up to 48 hours, potentially saving lives by enabling faster medical intervention.

Why it matters

Rapid diagnostic tools for acute conditions like sepsis could significantly reduce mortality rates by allowing clinicians to optimize treatment much earlier.

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A patient arrives at a hospital showing signs of sepsis, a deadly condition where the immune system attacks its own body after an infection. Sepsis kills 11 million people every year. Doctors must treat it within hours to save lives, but standard blood tests take up to 48 hours for results.

Last year, researchers reported a sensor platform capable of detecting multiple immune proteins linked to sepsis from a blood sample in real time. It was also compact enough for bedside use. The device was a protein biosensor — and it was based on six decades of research and technological development to read the body’s molecular signals at a speed compatible with acute medical needs.

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