Host-virus determinants of Ebola virus persistence in a human cerebral organoid model

Researchers have developed a human cerebral organoid model to study how the Ebola virus persists in the central nervous system. The study reveals that continuous infection of neurons and astrocytes drives local inflammation, providing insights into post-recovery health complications.
Why it matters
Understanding the mechanisms of viral persistence in immune-privileged sites is critical for developing treatments for Ebola survivors and preventing future outbreaks.
Nature Microbiology ( 2026 ) Cite this article
The content is a summary of scientific research published in a peer-reviewed journal.
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