Hormone ‘fingerprint’ found in endometriosis
Researchers at the University of Edinburgh have identified a unique 'hormone fingerprint' involving androgens in patients with endometriosis. This discovery could lead to a non-invasive diagnostic test, potentially replacing the need for surgical confirmation.
Why it matters
Endometriosis is often difficult to diagnose, and a non-invasive test would significantly improve patient outcomes and reduce the time to treatment.
A study has found people with endometriosis have a distinct pattern of hormones, with researchers saying the finding could transform diagnosis and treatment of the condition.
A team led by researchers at Britain’s University of Edinburgh found that those with endometriosis have differences in a group of androgens – so-called “male” hormones – compared with those without the condition.
They said the findings could lead to a simple, non-invasive route for diagnosis of the condition, which can take years before it is confirmed through surgery.
Estimated to affect around one in 10 women of reproductive age, endometriosis occurs when cells similar to the ones in the lining of the womb are found elsewhere in the body.
These cells can grow and change in response to hormones, leading to inflammation, pain and the development of scar tissue.
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