HIV i-Base: UKHSA continues to recommend 4CMenB vaccine against gonorrhoea in gay men
The UK Health Security Agency continues to recommend the 4CMenB vaccine for gay and bisexual men to prevent gonorrhoea, despite recent clinical trials failing to show significant protection. The medical community remains divided on the vaccine's efficacy, with some experts calling for further study.
Why it matters
This highlights the ongoing challenge of addressing public health crises when clinical trial results conflict with observational data.
On 31 May 2026, UKHSA published new guidance on the continued use of the 4CMenB vaccine in a sexual health programme aimed to reduce the incidence of gonorrhoea in gay and bisexual men.
The report provides a balanced overview of medical guidance and the conflicting scientific evidence surrounding it.
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