Heart stress based on NT-proBNP changes may improve CVD risk stratification
A study published in the Annals of Internal Medicine suggests that monitoring longitudinal changes in NT-proBNP levels can improve cardiovascular disease risk stratification in older adults. The research indicates that heart stress status is a significant predictor of mortality and CVD events.
Why it matters
This finding could lead to more precise preventative care strategies for aging populations by using biomarker tracking to identify high-risk individuals.
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Add as preferred source For community-dwelling older adults, longitudinal changes in N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations (heart stress [HS]) may improve risk stratification for cardiovascular disease (CVD) and mortality, according to a study published online Aug. 18 in the Annals of Internal Medicine .
Anping Cai, M.D., Ph.D., from Southern Medical University in Guangzhou, China, and colleagues examined the association of HS status, based on three-year changes in NT-proBNP concentrations, with the risk of total CVD and all-cause mortality in community-dwelling older adults free of prior CVD. Participants included 8,454 individuals without prior CVD who had NT-proBNP measured at trial enrollment and year 3. HS status was classified as persistently HS-free, HS remission, incident HS or sustained HS.
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