Giraffe Bio aims its bespoke biomolecules at the looming copper shortage

Startup Giraffe Bio has raised $6.4 million to develop bespoke biomolecules that help mining companies extract more copper from existing sites. By using engineered microbes in bioreactors rather than live bacteria, the company aims to improve recovery rates by up to 5%.
Why it matters
Improving copper extraction efficiency is critical for meeting the surging demand for minerals required by the global energy transition and AI data center infrastructure.
Between the AI data center boom and economy-wide electrification, the world will need a lot more copper. By 2040, copper supplies could fall 25% short of demand.
That’ll be a tall order for the mining industry, which boosts production mostly by opening new mines, which is a costly, luck-driven endeavor. Typically, just 0.3% of prospective mines pan out.
A new wave of critical minerals startups have been working on new ways to squeeze more copper out of existing mines using biotechnology, mostly by focusing on heap leaches, where microbes help separate minerals from waste. Endolith has created “Olympic caliber” microbes, Ceibo is working on its own strains, and Transition Metal Solutions has developed prebiotics to boost microbial activity.
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