Genetic trade-off between youth and longevity uncovered
Researchers have identified the vgll3 gene in killifish as a key factor in a biological trade-off where early-life growth and reproductive success come at the cost of accelerated aging and cancer risk. This study provides experimental evidence for the evolutionary theory of antagonistic pleiotropy.
Why it matters
Understanding the genetic links between development and aging could lead to new medical breakthroughs in managing age-related diseases and cancer.
edited by Sadie Harley , reviewed by Robert Egan
The article is a scientific report based on peer-reviewed research published in Nature Communications.
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