Genetic 'switches' could program 3D-printed bone tissue for blood vessel growth

by Ty Tkacik, Pennsylvania State University

edited by Sadie Harley , reviewed by Robert Egan

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Add as preferred source Micro-computed tomography, or a microscopic X-ray, of the regenerated bone taken by the research team. The top row of photos was taken at week three, and the bottom row was taken six weeks after implantation. The far right photo shows the regenerated bone facilitated by spheroids containing a combination of stem cells, which demonstrated higher bone density and bone coverage than tissues containing no spheroids. Credit: Ibrahim Ozbolat / Daniel Hayes An interdisciplinary team of engineers and chemists at Penn State has laid the groundwork for 3D printing spheroids—tiny clusters of living cells—capable of regenerating bone tissue in response to severe trauma or infections.