The American Journal of Managed Care·3 min read·hard

Genetic Analysis Links Insomnia Liability to Higher Inflammation Marker

G
Giuliana Grossi
Genetic Analysis Links Insomnia Liability to Higher Inflammation Marker
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A genetic study published in 'Sleep' suggests a link between insomnia and systemic inflammation, specifically identifying shared genetic markers. Researchers found evidence that insomnia may contribute to higher levels of C-reactive protein, a key inflammation indicator.

Why it matters

Understanding the biological link between sleep disorders and inflammation could lead to new therapeutic approaches for managing chronic health conditions.

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Genetic evidence suggests insomnia may help drive systemic inflammation, according to a study published online in Sleep.1 Researchers at Massachusetts General Hospital and the Broad Institute identified 125 genetic loci, or regions of the genome, shared between insomnia and C-reactive protein (CRP), a marker of low-grade inflammation. They found stronger support for an effect running from insomnia to CRP than the reverse.

CRP Is Higher in People With Insomnia

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