Fluid shear stress inhibits vascular endothelial cells proliferation via EGR1/Grem1 axis
Researchers have identified that fluid shear stress inhibits the proliferation of vascular endothelial cells by downregulating the EGR1/Grem1 signaling axis. This discovery provides new insights into the biological mechanisms underlying pulmonary hypertension.
Why it matters
Understanding the molecular pathways of pulmonary hypertension could lead to more effective therapeutic interventions for patients suffering from the condition.
Scientific Reports ( 2026 ) Cite this article
We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in