Fidji Simo steps down from leading OpenAI’s AGI work due to illness

Fidji Simo is stepping down from her full-time role as OpenAI's AGI chief to transition into a part-time advisory position. This decision follows a period of medical leave due to a chronic neuroimmune condition.
Why it matters
The departure marks another significant leadership change at OpenAI during a period of internal reorganization and strategic focus on agentic AI platforms.
OpenAI’s Fidji Simo is departing her full-time role as the company’s AGI chief and is transitioning to being a “part-time advisor,” she said on X.
The news follows Simo’s original announcement in April that she would take a few weeks of medical leave due to a neuroimmune condition, shortly after she had taken on the AGI chief title. (She had formerly been the company’s CEO of applications). Around the same time, COO Brad Lightcap also stepped down from his role to focus on “special projects,” and OpenAI CMO Kate Rouch also stepped down in order to focus on her health. Rouch planned to return to a “more narrowly scoped role” when her health allowed for it, Simo said at the time.
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