Fibrinogen discovery reshapes understanding of how wounds heal
Scientists have discovered that the blood-clotting protein fibrinogen stacks in multiple layers when exposed to air, overturning a 20-year-old scientific consensus. This finding could significantly improve treatments for clotting disorders and the design of medical biosensors.
Why it matters
Redefining fundamental biological processes can lead to breakthroughs in medical diagnostics and the treatment of respiratory and blood-related conditions.
edited by Sadie Harley , reviewed by Robert Egan
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Add as preferred source Visual abstract. Credit: Journal of the American Chemical Society (2026). DOI: 10.1021/jacs.6c11928 Scientists have redefined how the key blood-clotting protein fibrinogen behaves when it contacts air, overturning two decades of scientific consensus on wound healing. It is the culmination of more than a decade of international collaboration by Dr. Richard Campbell of The University of Manchester, Professor Juan Ruso of the University of Santiago de Compostela in Spain and Dr. Natalia Hassan of the Metropolitan Technological University in Chile.
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