Fast-ageing Placentas May Explain Pre-eclampsia Risks
Researchers from Flinders University have identified that premature placental ageing may be a key driver of pre-eclampsia. This discovery could lead to new biological treatments for the condition.
Why it matters
Pre-eclampsia is a major cause of maternal and infant mortality, and understanding its biological origins is critical for improving pregnancy outcomes.
For women diagnosed with pre-eclampsia, the only cure is often to deliver the baby - even if the pregnancy has not yet reached full term.
Pre-eclampsia affects up to 8% of pregnancies worldwide and contributes to about 16% of maternal deaths globally, making the condition one of pregnancy's most serious complications.
New research led by Flinders University, in collaboration with the Robinson Research Institute at Adelaide University, has uncovered clues about why pre-eclampsia occurs, finding that a placenta may age prematurely. Researchers have also identified the biological pathways that could eventually help protect mothers and babies.
Lead author Dr Anya Arthurs from Flinders Health and Medical Research Institute (FHMRI) says the study goes beyond identifying a damaged placenta to explain what may cause that damage.
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