Extending cryo-electron microscopy beyond water

Researchers at Tohoku University have developed a 'gradient blotting' technique to enable cryo-electron microscopy for materials in organic solvents like methanol. This method overcomes previous limitations in sample preparation, allowing for the observation of microscopic structures in non-aqueous environments.
Why it matters
This advancement allows scientists to study industrial materials like catalysts and drug-delivery systems in their native liquid states, potentially accelerating innovation in material science.
edited by Lisa Lock , reviewed by Andrew Zinin
The article is a straightforward report on scientific research without political or social framing.
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