Nature·4 min read·hard
Exploring the landscape of targetable alterations in patients with glioblastoma
A
Aquilanti, Elisa
✦AI Summary
This review examines the current therapeutic landscape for glioblastoma, noting that targeted treatments remain largely ineffective due to tumor heterogeneity and limited drug delivery to the brain. Researchers are exploring new strategies, including antibody-drug conjugates and liquid biopsies, to overcome resistance and improve patient outcomes.
Why it matters
Glioblastoma is one of the most lethal brain cancers, and identifying new molecular targets is critical for advancing survival rates in oncology.
Nature Reviews Clinical Oncology ( 2026 ) Cite this article
sciencehealth
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