Experimental cancer treatment disrupts cell communication to suppress tumor growth in animal tests
Researchers have developed a new cancer treatment platform that disrupts the communication network between cancer cells and their surrounding microenvironment. By targeting EGFR, the treatment suppresses tumor growth and metastasis in animal models.
Why it matters
This approach offers a novel strategy for cancer therapy by addressing the supportive role of the tumor microenvironment, potentially overcoming resistance to conventional treatments.
edited by Sadie Harley , reviewed by Robert Egan
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Add to Preferred Sources Ctx-ETAC suppresses EV secretion, disrupts cancer-CAF communication, and induces CAF and macrophage reprogramming, ultimately inhibiting tumor progression and metastasis through EV network collapse. Credit: Eun Hye Kim, et al. Journal of the American Chemical Society https://doi.org/10.1021/jacs.6c11538 A research team has developed an anticancer treatment platform that simultaneously targets cancer cells and the surrounding cells that support them while blocking communication between the two.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in