Erectile dysfunction drug linked to higher glaucoma risk

A multinational study published in the British Journal of Ophthalmology suggests that long-term use of tadalafil, commonly used for erectile dysfunction and enlarged prostate, may increase the risk of glaucoma. Researchers recommend that patients on long-term daily doses undergo regular eye examinations.
Why it matters
This finding provides critical health guidance for a large population of men using common medications for chronic urinary symptoms.
<p data-start="76" data-end="319">Men taking tadalafil (Cialis) long term to treat urinary symptoms associated with an enlarged prostate may face a higher risk of developing glaucoma, according to a large multinational study.</p>
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<p data-start="321" data-end="609">The findings prompted researchers to recommend baseline eye examinations and ongoing ophthalmic monitoring for patients prescribed long-term tadalafil, particularly those with existing glaucoma risk factors such as ocular hypertension, high myopia or a family history of the disease.</p>
Researchers from the National Taiwan University Hospital and collaborating institutions in Taiwan reported results in the <em><a href="https://bjo.bmj.com/content/early/2026/07/28/bjo-2026-329957" target="_blank" rel="noopener">British Journal of Ophthalmology</a> </em>on 28 July 2026.
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