Engineering enzymes with potential against ALS and Parkinson's disease
Researchers at Washington University in St. Louis have developed a high-throughput method to rapidly produce and screen engineered "disaggregase" enzymes, specifically Hsp104 from yeast. These enzymes are capable of breaking down misfolded proteins linked to neurodegenerative diseases like ALS and Parkinson's disease.
Why it matters
This scientific advance could significantly accelerate the discovery and development of new therapeutic treatments for devastating neurodegenerative conditions by making the identification of effective enzymes much faster and more efficient.
by Chris Woolston, Washington University in St. Louis
Factual reporting of scientific research findings from a university source, republished by a science news aggregator.
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