Engineered enzymes forge carbon-carbon and carbon-nitrogen bonds with high selectivity

Researchers at the University of Manchester have developed engineered enzymes capable of creating carbon-carbon and carbon-nitrogen bonds with high selectivity. This breakthrough offers new methods for biocatalysis in the production of pharmaceuticals and advanced materials.
Why it matters
This advancement could significantly improve the efficiency and sustainability of chemical manufacturing processes.
by Enna Bartlett, University of Manchester
edited by Swati Mestri , reviewed by Robert Egan
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Add as preferred source Credit: University of Manchester Researchers from the Manchester Institute of Biotechnology, including Dr. Zachary Birch-Price and professor Anthony Green, have developed a new family of engineered enzymes that can create several different types of chemical bonds used to build complex molecules. This work demonstrates how artificial enzymes can be adapted to carry out a broad range of carbon-carbon (C-C) and carbon-nitrogen (C-N) bond-forming reactions with high selectivity, offering new possibilities for biocatalysis.
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