Engineered coating lets mitochondria retain their ability to produce energy
Researchers from Politecnico di Milano and FINCB have successfully coated mitochondria with metal-organic frameworks (MOFs) without hindering their energy-producing functions. This breakthrough could lead to new treatments for rare mitochondrial diseases by protecting these delicate cellular structures.
Why it matters
Advancements in mitochondrial engineering offer potential therapeutic pathways for currently untreatable genetic diseases affecting high-energy tissues like the brain and muscles.
edited by Gaby Clark , reviewed by Robert Egan
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Add as preferred source Coating mitochondria with Metal-Organic Frameworks (MOF) may help them performing specific functions, while still retaining their ability to produce energy. Credit: Politecnico di Milano Researchers have coated mitochondria with innovative materials without compromising their function, according to a study by IRCCS Fondazione Istituto Neurologico Carlo Besta (FINCB) and Politecnico di Milano. The research was conducted as part of the BraiNs joint laboratory, inaugurated in 2023.
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