Emerging SARS-CoV-2 sublineage RE.2.2 displays distinct structural features
Researchers from the Chinese Academy of Sciences have identified structural features of the SARS-CoV-2 sublineage RE.2.2. The study reveals that this variant has enhanced binding to human ACE2 receptors and a distinct antibody escape profile.
Why it matters
Understanding the evolution and structural properties of new COVID-19 variants is critical for public health monitoring and vaccine development.
by Zhang Nannan, Chinese Academy of Sciences
edited by Sadie Harley , reviewed by Robert Egan
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Add as preferred source Structural features, receptor recognition, and glycosylation profiling of SARS-CoV-2 sub-variant BA.3.2.2/RE.2.2. Credit: Prof. Gao George Fu's group Researchers from the Institute of Microbiology of the Chinese Academy of Sciences (IMCAS) have characterized the structural and functional properties of the emerging SARS-CoV-2 sublineage BA.3.2.2 by studying RE.2.2, the lineage designation for the BA.3.2.2 branch gaining prevalence after prolonged low detection in European surveillance datasets.
The study, conducted by Prof. Gao George Fu's laboratory at the Institute of Microbiology of the Chinese Academy of Sciences (IMCAS), was published in PNAS .
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