Electroencephalographic gamma correlates with pain intensity attenuation in a prospective longitudinal study using an AI-powered digital device for pain self-management

A longitudinal study using the AI-powered Paindrainer app found a correlation between increased EEG gamma oscillations and reduced pain in patients with chronic back or neck pain. While the results are promising, the study notes that statistical significance was not maintained after correcting for multiple comparisons.
Why it matters
This research explores the intersection of digital health tools and neuro-biomarkers, potentially offering new ways to objectively measure and manage chronic pain.
Scientific Reports ( 2026 ) Cite this article
We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.
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