Effect of a digital intervention on mental health symptoms in adults with chronic conditions: A three-arm randomized controlled trial
A randomized controlled trial evaluated the effectiveness of a digital intervention for managing anxiety, depression, and fatigue in adults with chronic conditions. The study compared self-directed digital programs with those supplemented by human support.
Why it matters
Digital health interventions could provide scalable, accessible mental health support for the millions of people living with chronic medical conditions.
Anxiety, depression, and fatigue affect >50% of adults across a range of chronic medical conditions, leading to reductions in quality of life. Digital symptom management interventions may address this burden, but clinical trial evidence across diverse conditions is limited, and the added value of human support remains uncertain. This study aimed to determine whether a multicomponent digital intervention, delivered with or without human support, reduces anxiety and depression compared with usual care at 12 weeks in adults with chronic medical conditions, and whether human-supported delivery outperforms self-directed delivery.
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