Early Fibrinogen Predicts DVT Risk After Hip Fracture

A retrospective study has identified that elevated fibrinogen levels measured within 24 hours of admission can predict the risk of deep venous thrombosis (DVT) in elderly hip fracture patients. The study suggests that combining fibrinogen with other markers improves diagnostic accuracy.
Why it matters
Early identification of DVT risk in surgical patients can lead to better preventative care and improved patient outcomes.
EARLY fibrinogen measurement was associated with an increased risk of deep venous thrombosis in older adults admitted with hip fracture, according to a new retrospective cohort study.
Deep venous thrombosis (DVT) is a frequent and serious complication following hip fracture in older adults.
Researchers found that patients with higher fibrinogen concentrations within 24 hours of admission were significantly more likely to develop DVT than those with lower levels.
The study evaluated 234 patients aged 60 years and older who were admitted with hip fracture between January 2020 and June 2023.
Bilateral lower extremity Doppler ultrasound was performed within 24 hours of admission, while blood samples were collected before pharmacological thromboprophylaxis was initiated.
Among the study population, 50 patients developed DVT, corresponding to an incidence of 21.4%.
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