Detroit Lions updated depth chart: Week 2 at Bills

Ahead of every Detroit Lions game in 2026, we will provide readers with an updated depth chart of the team’s roster based on information gathered throughout the week. In Week 2, the Detroit Lions will travel to Buffalo to take on the Bills and christen Highmark Stadium.

To help you prepare for this matchup, we have a detailed Lions depth chart that ranks all players and provides the latest news on roster moves, injury statuses, and other relevant developments. For your viewing experience, we have listed the players’ numbers (in parentheses; note: several players changed their numbers after the preseason), bolded the projected starters, and added an asterisk* after the rookies’ names.