Compound from pomegranates, walnuts and berries boosts heart function in tests
Researchers at King's College London have discovered that urolithin A, a compound found in pomegranates and walnuts, significantly improves heart function in animal models. The study suggests a potential new pathway for treating heart failure with preserved ejection fraction (HFpEF).
Why it matters
HFpEF is a common and difficult-to-treat form of heart failure; this discovery could lead to new dietary or pharmaceutical interventions.
A compound made naturally by the body after eating certain foods may offer a new way to tackle one of the more difficult forms of heart failure. In early experiments, urolithin A, a substance linked to foods including pomegranates, walnuts and some berries, helped stiff heart tissue relax, reduced scarring and limited harmful changes to heart muscle. Researchers at King's College London found that the compound improved measures of heart function by as much as 80% in animal models. The results, while still far from a treatment for people, point to a previously unexplored biological pathway that could eventually be targeted in cardiovascular disease. Scroll down to read the details.A heart that can pump, but cannot relaxThe study, published in Science Advances and funded by the British Heart Foundation states that the research focuses on heart failure with preserved ejection fraction, or HFpEF.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in