Clinical aging clocks uncover different metabolic turning points for men and women
A study published in Nature Aging identifies distinct metabolic turning points in men and women, with men experiencing changes in their 30s and 40s and women in their 50s and 60s. The research suggests that routine clinical measurements can effectively track physiological aging and identify potential interventions.
Why it matters
Understanding sex-specific aging trajectories could lead to more personalized preventative healthcare and better management of age-related diseases.
edited by Gaby Clark , reviewed by Robert Egan
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Add as preferred source Overview of the study design and clinical measurements. Credit: CNCB Aging varies markedly among individuals and between sexes, yet the timing of major physiological transitions and the factors driving these changes have not been well understood.
However, a new study suggests that routine clinical measurements, which are widely available and repeatedly collected, may provide a practical way to assess aging at a population scale.
The study, published in Nature Aging on Aug. 25, analyzed routine clinical data from 104,208 adults ages 18–98 across three centers in China. It established sex-specific clinical aging clocks based on 172 commonly measured indicators and provided a practical approach to estimating physiological aging from routine health examinations.
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