Cialis linked to higher glaucoma risk in large study
A large study suggests that long-term use of the erectile dysfunction drug tadalafil (Cialis) for urinary symptoms may be linked to an increased risk of glaucoma. Researchers recommend closer eye health monitoring for men using the medication daily over extended periods.
Why it matters
This finding could impact clinical prescribing habits for millions of men using PDE5 inhibitors for benign prostatic hyperplasia.
A widely used erectile dysfunction medication may be associated with a greater risk of glaucoma when taken long-term to relieve urinary symptoms caused by an enlarged prostate, according to a large comparative study published online in the British Journal of Ophthalmology .
The findings suggest that men who use tadalafil (Cialis) over extended periods for these symptoms may benefit from closer monitoring of their eye health. Researchers say this may be especially important for people who already have glaucoma risk factors, including a family history of the disease or elevated pressure within the eye (ocular hypertension).
Tadalafil belongs to a group of medications known as phosphodiesterase type 5 inhibitors (PDE5i), the same drug class that includes sildenafil (Viagra). These medications are widely used for erectile dysfunction, while tadalafil is also prescribed for urinary problems associated with an enlarged prostate.
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