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Childhood Abuse Leaves Scar On Brain, Study Finds

Childhood Abuse Leaves Scar On Brain, Study Finds
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A large-scale neuroimaging study led by UCLA researchers has identified physical changes in the brain associated with childhood abuse. The study found that maltreatment correlates with variations in cortical thickness and volume, particularly in young women.

Why it matters

Understanding the neurobiological impact of childhood trauma is essential for developing better mental health treatments for PTSD and depression.

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Childhood abuse leaves a scar on the brain, a new neuroimaging study led by UCLA psychologists has shown. The researchers found associations between the severity of different maltreatment exposures and cortical thickness, surface area and subcortical volume based on MRI images of individuals. The effect was more pronounced in young women than in men or in children. The study is the largest of its kind to examine the neurobiological legacy of childhood maltreatment across a diverse, global sample of people.

"We know that childhood maltreatment is a major risk factor for many stress-related disorders, including major depressive disorder and posttraumatic stress disorder, and we wanted to know if there was what amounted to a neurobiological scar associated with these adverse experiences," said UCLA psychology professor Tiffany Ho, the corresponding author of the study, which is published in the journal Biological Psychiatry.

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