Cancer-promoting proteins may make tumors easier to spot... but also help them evade immune attack
Researchers have discovered that the cancer-promoting proteins YAP and TAZ can make tumors more visible to the immune system while simultaneously suppressing immune attacks via PD-L2. This dual effect may explain why certain patients respond better to immune checkpoint inhibitor therapies.
Why it matters
Understanding these protein interactions could lead to more effective cancer treatments and better patient selection for immunotherapy.
edited by Sadie Harley , reviewed by Robert Egan
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Also covering this story
One other newsroom covered this event. We read that version too.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in