Building big with DNA gets a software upgrade

Researchers are advancing DNA nanotechnology by developing methods to create larger, more stable 3D DNA megastructures. These structures could eventually be used for complex applications like targeted drug delivery and advanced electronic devices.
Why it matters
Scaling DNA nanotechnology could revolutionize fields ranging from medicine to computing by allowing for precise, nanoscale engineering.
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Add as preferred source Megastructure design gallery. Credit: Nature Communications (2026). DOI: 10.1038/s41467-026-75175-6 Forty-four years ago, Nadrian Seeman published his groundbreaking ideas on using DNA as a structural material, expanding DNA's significance far beyond its role as a carrier of genetic information. Since then, the steadily growing field of DNA nanotechnology has seen numerous innovations. One was the DNA origami technique, which enables researchers to fold a single long strand of DNA into a desired 2D or 3D shape.
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