Brain organoids uncover how primates develop different brain shapes

edited by Sadie Harley , reviewed by Robert Egan

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Add as preferred source Cross-section of a common marmoset brain organoid. Magenta: progenitor cells that have doubled their genetic material in the last six hours; blue: cell nuclei; yellow: surface of the ventricle. Credit: Lidiia Tynianskaia - German Primate Center Most primate species have relatively large brains with surfaces marked by pronounced bulges and furrows. This is not the case with common marmosets (Callithrix jacchus). The brains of these small monkeys are smooth and virtually unfolded.

Researchers at the German Primate Center (DPZ)—the Leibniz Institute for Primate Research in Göttingen—investigated which cellular processes during embryonic development cause the marmoset brain to develop differently from a certain stage onward.