Brain enzyme caught doing something unexpected-it builds polysialic acid on itself

Researchers at Nagoya University discovered that the brain enzyme ST8Sia5 has a unique ability to build polysialic acid chains on itself. This finding challenges previous assumptions about how these sugar chains, which are vital for brain development and memory, are regulated.
Why it matters
Understanding this enzyme's self-regulating mechanism provides new insights into neural development and potential therapeutic targets for brain-related disorders.
edited by Gaby Clark , reviewed by Robert Egan
The article is a straightforward report on a scientific discovery published in a peer-reviewed journal.
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