Blood proteins may offer new clues to gut health in celiac disease

Researchers at the University of Oslo have identified 24 blood proteins that may serve as biomarkers for celiac disease activity. This discovery could help patients and doctors better monitor intestinal health beyond current diagnostic limitations.
Why it matters
Improved biomarkers could significantly enhance the management of autoimmune conditions by providing clearer data on treatment efficacy.
edited by Gaby Clark , reviewed by Andrew Zinin
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Add to Preferred Sources Inflammatory protein profiles in untreated and treated celiac disease. Credit: Gastroenterology (2026). DOI: 10.1053/j.gastro.2026.07.033 Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.
The condition is treated by avoiding gluten entirely. Although many people with celiac disease adhere carefully to a gluten-free diet, current blood tests do not always show clearly whether inflammation or intestinal damage persists.
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