Barcelona team develops AI that detects ageing in blood stem cells
Researchers in Barcelona have developed an AI tool called ChromAgeNet that identifies biological ageing in blood stem cells by analyzing 3D DNA structures. The tool uses explainable AI to help scientists understand the specific structural changes in chromatin that occur as cells age.
Why it matters
This technology could lead to new medical interventions that slow cellular decline and improve the body's regenerative capabilities.
Barcelona team develops AI that detects ageing in blood stem cells Ageing gradually undermines the body's ability to regenerate, severely affecting the production of blood cells. In this race against the biological clock, analysing changes in blood stem cells is crucial to opening the door to interventions that can slow their decline and restore their original function.
A scientific team in Barcelona has developed ChromAgeNet, an artificial intelligence tool that detects ageing in blood stem cells by analysing the three-dimensional structure of their DNA.
Published in the journal "Aging Cell", the research, led by Maria Carolina Florian (IDIBELL) and Paula Petrone (BSC-CNS/ISGlobal), shows that the organisation of chromatin contains information that makes it possible to distinguish cells from young and aged mice .
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