Autoantibodies could shape cancer risk, growth and response to immunotherapy

Researchers are investigating the role of autoantibodies in cancer risk, growth, and immunotherapy response. The study, led by the ATLAS team, aims to determine if these immune proteins can be used to predict or treat cancer.
Why it matters
Understanding the immune system's interaction with cancer could lead to breakthroughs in personalized medicine and more effective cancer prevention strategies.
edited by Lisa Lock , reviewed by Andrew Zinin
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Add as preferred source Credit: Pixabay/CC0 Public Domain Scientists have long sought to understand why some people with no known risk factors develop cancer while others with significant risk never do. The answer may lie in immune proteins known as autoantibodies (auto-Abs), suggests a commentary published in Cell co-authored by a team that includes Jean-Laurent Casanova, M.D., Ph.D., a professor in the Center for the Genetics of Host Defense and Children's Medical Center Research Institute at UT Southwestern (CRI).
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