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Nature·4 min read·hard

Association of pre-existing cardiovascular disease with cardiovascular and clinical outcomes in patients receiving immune checkpoint inhibitors

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Alfehaid, Lama
Association of pre-existing cardiovascular disease with cardiovascular and clinical outcomes in patients receiving immune checkpoint inhibitors
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A retrospective study of 608 patients in Saudi Arabia found that pre-existing cardiovascular disease is a significant independent predictor of cardiovascular events in cancer patients receiving immune checkpoint inhibitors. The findings suggest that patients with baseline heart conditions face a substantially higher risk of complications during immunotherapy.

Why it matters

As immunotherapy becomes a standard cancer treatment, identifying high-risk patients is crucial for managing potential life-threatening cardiovascular side effects.

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Scientific Reports ( 2026 ) Cite this article

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.

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