Nature·4 min read·hard
Ameliorating calcium homeostasis improves longevity and healthspan in progeroid and naturally aged mice
✦AI Summary
Researchers have discovered that the antidepressant Mianserin can improve calcium homeostasis, potentially extending the healthy lifespan of progeroid and naturally aged mice. The study identifies a specific cellular pathway involving S100A6 and DNA damage that contributes to aging.
Why it matters
This finding offers a potential pharmacological strategy for treating age-related disorders and extending human healthspan.
Nature Communications ( 2026 ) Cite this article
healthscience
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The article is a summary of scientific research findings and does not contain political or social bias.
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