Alzheimer Disease Blood Biomarkers After TBI

A study of older veterans indicates that a history of traumatic brain injury (TBI) significantly reduces the accuracy of blood-based Alzheimer's disease biomarkers. Researchers found that sensitivity for detecting amyloid positivity drops as the severity of the TBI increases.
Why it matters
This finding suggests that current diagnostic tools for Alzheimer's may need adjustment for patients with a history of head trauma to avoid misdiagnosis.
ALZHEIMER disease blood biomarkers may be less accurate in veterans with prior traumatic brain injury.
The article reports on scientific findings from a clinical study using objective data and neutral terminology.
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