AI is among 17 potentially ‘catastrophic threats’ that researchers say require targeted action

A new report in The Lancet identifies 17 catastrophic threats to global health, including nuclear conflict and the malicious use of AI. Researchers emphasize that while these risks are severe, proactive leadership can mitigate their impact.
Why it matters
The study underscores the urgent need for global policy intervention to address existential risks that could significantly reduce human life expectancy.
More than a dozen “interconnected catastrophic threats” pose significant risk to global health and wellbeing through the remainder of the 21st century, researchers say – including the potential for extinction. But targeted action from world leaders can help avoid worst-case scenarios. Using data from the Institute for Health Metrics and Evaluation’s Global Burden of Disease study, a commission of 35 leaders from various industries forecast the total years of good health that could be lost by the global population by due to sickness, disability or premature mortality from a range of threats. Their findings, published in the journal The Lancet, identify 17 threats that pose the greatest danger – but also have the potential for realistic intervention. The threats include health conditions and behaviors – such obesity, high blood pressure, smoking and mental health – as well as economic conditions, environmental change, technology and conflict.
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