Age and sex shape cancer immunity, mouse experiments and human data suggest
A study published in Nature Aging reveals that biological sex and aging significantly influence immune system function and cancer response. The research suggests that age-related changes in T cell immunity differ between men and women.
Why it matters
Understanding these differences could lead to more personalized cancer immunotherapy treatments based on a patient's biological profile.
edited by Gaby Clark , reviewed by Robert Egan
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Add to Preferred Sources Credit: Moe Magners from Pexels A new study published in Nature Aging combines mouse experiments and human data sets to explore how biological sex and aging shape cancer immunity, with implications for immunotherapy responses. Lutz Menzel, Ph.D., formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, is the lead author, and Tim Padera, Ph.D., of the Mass General Brigham Cancer Institute, is the senior author. The paper is titled "Lymph node contraction links sex-biased naive CD8 T cell decline to compromised antigen recognition during middle age."
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in