Adverse pregnancy outcomes and long-term risk of peripheral artery disease: A cohort study
A large-scale Swedish cohort study of over 2.2 million women found that adverse pregnancy outcomes are linked to a significantly higher long-term risk of peripheral artery disease. The research suggests that these pregnancy complications serve as early indicators for future cardiovascular health issues.
Why it matters
Identifying these links allows for better early risk stratification and clinical intervention to improve long-term cardiovascular outcomes for women.
Women with adverse pregnancy outcomes have higher subsequent cardiovascular risks, but their long-term risks of peripheral artery disease (PAD) and potential causality are unclear. A better understanding of such risks is needed to improve early risk stratification, clinical care, and long-term cardiovascular health. We sought to determine long-term risks of PAD associated with 5 major adverse pregnancy outcomes in a large population-based cohort, and to assess for familial confounding using co-sibling analyses.
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